When late night comedians are struggling to keep it together, you know it's real.

Seth Meyers opened his show last night by dropping straight into the Donald Trump's election win and exposed just how raw the pain was for many Americans left dumbfounded by the result.

Meyers talked about his own mother and the lost prospect of the first female president of the United States and got visibly teary while relating how excited they had been about the idea of President Hillary Clinton and how the future first female president now exists out there somewhere.

"We don’t know who you are, but I imagine this moment today will be a defining one for you," he said. "One that will make you work harder, and strive farther, and whoever you are, I hope I live to see your inauguration."

Here's hoping, Seth.